FREE10BOOK

Research on purine derivatives as potent and selective modulators of physiologic functions has moved to center stage. This volume covers the biology and chemistry of purines and of their receptors broadly under these section headings: - Adenosine Receptors and Effector Systems - Adenine Nucleotide Receptors and Effector Systems - Phosphodiesterase Enzymes and Inhibitors The presentations focus on the potential development of clinically useful drugs and powerful agents that activate or block purinergic receptors or that inhibit phosphodiesterases. Xanthines (caffeine and theophylline) represent one class of such agents. This volume is for pharmacologists, biochemists, and medical chemists in research labs of universities, gov- ernment, and the pharmaceutical industry. Product details Format Hardback ...

The study of marine plankton has traditionally focused on those or ganisms that appeared to have obvious ecological significance in un derstanding the major patterns of biological productivity, trophic relations, community structure, and the dynamic interaction of living things with the physical environment. Not infrequently, this thrust has centered on the apparently most abundant and/or larger members of the plankton community, including significant primary producers such as the diatoms, nonthecate algae, and flagellates, or the major con sumers--copepods, gelatinous metazoa, and other abundant metazoan invertebrates. Consequently, some of the less well recognized but also abundant microzooplankton have been given less attention. The radio laria, although widely studied as fossils by micropaleontologists, have in modem times. This is la been relatively neglected by biologists mentable given their widespread distribution in the oceans, remarkably complex form, and not infrequently loc...

This is a comprehensive tool covering all manifestations of antimicrobial resistance, with viral, bacterial, parasitical and fungal resistance each given a dedicated section. The underlining molecular mechanisms, which depend not only on the microbe, but on the specific drug (target), are highly diverse, and are covered in great detail. This work also discusses and compares the biological, biochemical and structural aspects of resistance and its evolution. Product details Format Mixed media product | 606 pages Dimensions 155 x 235mm ...